Skin epidermal cells as well as those of the respiratory system are constantly exposed to air due to their location in the body. Thus, for health-risk assessment, it is important to characterize the response of these cells to cosmetics, tobacco products, etc., in an air-liquid interface (ALI) culture. Along with exposure to the elements, these cells are also subject to mechanical strains during respiration as well as in motor movement. Instron-TGT provides a complete solution for tissue culture and testing in ALI through the DermiGen Tension Compression System. The system is equipped with a bioreactor capable of cell/tissue culture at ALI and a mechanical stimulator for static as well as oscillatory load application. DermiGen is ideal for pharma, contract research organizations, the tobacco industry, and those working on cosmetic testing. The system is also aimed at research labs working on developing artificial skin models for in-vitro toxicity testing as well as labs focused on respiratory biology.